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Ramamurthy Mahalingam
| Research Area | Selected Publications | Lab Members |
 |
Title | Associate Professor |
| Office | 355A NRC | |
| Phone | 405-744-6207 | |
| Degree | Ph.D. Genetics. 1998. Clemson University, Clemson, SC. | |
| Website |
Oxidative signaling in plants
Oxidative signaling mediated by reactive oxygen species (ROS) is a central component of the plant responses to biotic and abiotic stresses. Identifying and characterizing key genes and metabolites involved in ROS perception and signaling is the goal of this research. Understanding the oxidative signaling pathway will provide rational targets for improving tolerance to multiple stresses in plants. We are using Arabidopsis thaliana and Medicago truncatula as model plants. Ozone, a major atmospheric pollutant and global climate change factor is our current emphasis. This multi-disciplinary research entails functional genomics, bioinformatics, genetics, biochemistry and molecular biology. The knowledge gained from these model systems will ultimately be useful in translational research for engineering crop plants with improved tolerance to multiple stresses.
Michael Puckette, Lila Peal, Jarrod Steele, Yuhong Tang and R. Mahalingam. 2009. Ozone responsive genes in Medicago truncatula: Analysis by suppression subtraction hybridization Journal of Plant Physiology (doi:10.1016/j.jplph.2009.01.009)
Puckette, M., Tang, Y., and Mahalingam, R. 2008. Transcriptomic changes induced by acute ozone in resistant and sensitive Medicago truncatula accessions. BMC Plant Biology 8:46.
Mahalingam, R., Jambunathan, N., and Penaganti, A. 2007. Pyridine nucleotide homeostasis in plant development and stress. Invited Review. International Journal of Plant Developmental Biology 1: 194-201.
Puckette, M, H. Weng and Mahalingam, R. 2007. Physiological and biochemical responses to acute ozone-induced oxidative stress in Medicago truncatula. Plant Physiology and Biochemistry. 40:70-79.
Jambunathan, N., and Mahalingam, R. 2006. Analysis of Arabidopsis Growth Factor Gene 1 (GFG1) encoding a nudix hydrolase during oxidative signaling. Planta, 224:1-11.
Mahalingam, R., N. Jambunathan, S.K. Gunjan, H. Weng and P. Ayoubi. 2006. Analysis of oxidative signaling induced by ozone in Arabidopsis. Plant Cell and Environment. 29:1357-1371.
Mahalingam, R.,* N. Shah, A. Scrymgeour and N. V. Fedoroff. 2005. Temporal evolution of Arabidopsis oxidative stress response. Plant Molecular Biology. 57:709-730. (*corresponding author).
Mahalingam, R. and N. V. Fedoroff. 2003. Stress response, cell death and signaling: the many faces of ROS. Physiologia Plantarum 119:56-68. (Invited Review).
*Mahalingam, R., A. Gomez, N. Eckardt, N. Shah, P. Day, A.G. Garcia, R. Raina and N. V. Fedoroff. 2003. Characterizing the stress/defense transcriptome of Arabidopsis Genome Biology, 4: R20. (*Highly Accessed Article according to BioMed Central)
Raina, S., R. Mahalingam, F. Chen and N. Fedoroff. 2002 Using the Arabidopsis geneome sequence database for rapid mapping of Ds transposon insertions. Plant Molecular Biology 50:93-110.
Mahalingam, R, and N. V. Fedoroff. 2001. Screening insertion libraries for mutations in many genes simultaneously using DNA microarrays. Proceedings of the National Academy of Sciences, 98:7420-7425.
Mahalingam, R. and H. T. Knap. 1999. Polygalacturonase in Glycine max - Heterodera glycines interactions. Molecular Plant Microbe Interactions, 12: 490-498.
Tomkins, J. P., R. Mahalingam, H. Smith, J. L. Goicoechea, H. T. Knap and R. A. Wing. 1999. A bacterial artificial chromosome library for soybean PI 437654 and identification of clones associated with cyst nematode resistance. Plant Molecular Biology 41: 25-32.
Mahalingam, R., H. T. Knap and S. A. Lewis. 1998. Inoculation method for studying early responses to Glycine max to Heterodera glycines. Journal of Nematology, 30: 237-240.
Wang, G., R. Mahalingam and H. T. Skorupska. 1998. (C-A) and (G-A) anchored simple sequence repeats (ASSRs) generated polymorphisms in soybean, Glycine max (L.) Merr. Theoretical and Applied Genetics 96: 1086-1096.
Lila Peal (Ph.D. student)
Anuradha Penaganti (Ph.D. student)
Xin "Justin" Zeng (Ph.D. student)
Aparna Kakani (Postdoctoral Fellow)
Recent Graduates:
Michael Puckette
Kim Winkelman
Anuradha Penaganti
